02395nas a2200229 4500008004100000245008000041210006900121260001600190300001100206490000600217520169000223653002101913653002101934653001501955653001601970653001101986653002401997653002902021100002502050700002802075856006202103 2020 eng d00aChronic Diseases Therapeutic Interchanges Drug Therapy: A Narrative Reviews0 aChronic Diseases Therapeutic Interchanges Drug Therapy A Narrati cAugust 2020 a98-1020 v93 a

Objective: To review the chronic diseases (gastrointestinal disorders, rheumatic arthritis etc.) therapeutic interchanges drug therapy. Methods: It is an extensive search, or fifty databases included the following through the Saudi Digital Library (SDL) searching engine. It included the various types of studies (meta-analysis, randomized controlled studies and observational studies) in the English language with human study only for the update May 2017. The search in terms of therapeutic interchange, medication, therapy and type of disease or medication based on therapeutics class of anti-psychiatric. The medication list and switch from one drug to alternative based on the literature found the search that has included comparative safety, efficacy and cost of the type of medication for each disease and national or international evidence-based guidelines. Results: The total number of studies after an extensive search with a specific term search was 487 studies. Of those, there were 107 duplicated studies, and 380 studies included for future evaluation. After evaluation, there were 19 studies about therapeutic interchange of chronic medications (Rheumatoid arthritis (RA) or Gastrointestinal disorder (GIT). Of those 19 studies, eight studies included for evaluation. Conclusion: Gastrointestinal and rheumatic arthritis medications, therapeutic interchange more practical and prevent the economic burden on healthcare systems. The implementation of therapeutic interchange of those medications is highly recommended at healthcare institutions in the Kingdom of Saudi Arabia.

10aChronic diseases10aGastrointestinal10aLiterature10aMedications10aReview10aRheumatic arthritis10aTherapeutic interchanges1 aAlomi, Yousef, Ahmed1 aBahadig, Faiz, Abdullah uhttps://www.ijphs.org/article/2020/9/3/105530ijpcs2020919